Know what exists, what qualifies, and what is still missing.

Can answer now

Which disease, donor, tissue and cell-state contexts are represented well enough to frame a DMD question.

Cannot answer alone

Whether one candidate perturbation changes a DMD muscle outcome.

Model or experiment handoff

Open Disease Atlas or Cell Browser before selecting a perturbation.

Can answer now

Which observed perturbation substrates and contextual screens are reusable for baseline, transfer or assay design.

Cannot answer alone

A calibrated DMD rescue, toxicity or fusion prediction without matched disease-context outcomes.

Model or experiment handoff

Open Dataset Cards, then ask the target in Virtual Cell.

Can answer now

Which model runs executed, which benchmarks are permanent controls and which task gates failed or remain locked.

Cannot answer alone

A disease-conditioned counterfactual when the required outcome edge is absent.

Model or experiment handoff

Open ModelRun Registry or Benchmark Center before interpreting model-like outputs.

Can answer now

Which experiment would convert an evidence gap into a reusable outcome object.

Cannot answer alone

A positive or negative biological effect before the registered study exists.

Model or experiment handoff

Use Planner or Study Cards to freeze assay, controls, endpoint and decision rule.

Same-assay response substrate and permanent baseline context.

Patient-derived and corrected cellular reference with biological units preserved.

Healthy-myoblast fusion perturbation evidence; contextual, not DMD replication.

Unperturbed human differentiation reference across physical time.

Non-muscle CRISPRa method calibration; no inherited DMD claim.