File, schema, identity, and governance checks for the frozen public objects.
Public scientific-resource status
What is public, what is pending, and what remains scientifically locked.
This page separates byte-level integrity, external publication authorization, and scientific validation. Passing one category never silently unlocks another.
This source-bundled record describes scientific objects and authorization gates. It is not a self-asserted hosting deployment receipt; provider version, content commit, and deployment time must be verified after rollout.
- Current release
- v1.2.0-measured-dmd-evidence
- Evidence freeze
- 2026-08-03
- Interface build
- EA-20260817-57
- Presentation candidate
- sites-scoped-batch-compare-20260904
- Formal database v1
- Not yet authorized
DOI, data licence, code licence, and final stewardship metadata remain pending.
The next value-creating step is a registered DMD myogenic perturbation outcome.
The prospective DMD prediction layer remains locked.
External publication gates
Four real inputs still control formal release identity.
DOI for the unchanged canonical archive
pending external actionApproved data licence identifier and text
pending institutional approvalApproved code licence identifier and text
pending institutional approvalApproved maintainer, affiliation and contact metadata
pending author inputOnly after all four external gates are structurally complete and author/institution authorization is recorded may the site label be changed to formal v1.0. That change still does not unlock P1 or P2 prediction claims.
Source-accession ledger
Datasets registered in the v1.1 catalog (5).
| Dataset | Biological context | Scale / modality | Source and terms | Typed record |
|---|---|---|---|---|
| NMDVCELL-HEPG2-CRISPRIObserved HepG2 CRISPRi candidate responses | Context-limited; not DMDHepG2 cell line | pooled perturbation response aggregate21 governed candidate aggregates | Open internal-release-substrateInternal release licence pending institutional approvalSource verification: recorded | Dataset CardJSONBASELINE READY SAME CONTEXT ONLYBoundary: Dataset registration does not convert context evidence into DMD perturbation-response outcome. |
| GSE293514Human myoblast fusion CRISPR screen | Muscle context; not DMD rescuehuman myoblast fusion screen | screen endpoint and validation workbooks7,197 screen genes; 250 hits; 125 individually validated genes | Open GSE293514Source paper DOI 10.1038/s41467-025-67583-xSource repository and publication terms apply; verify at accessionSource verification: required | Dataset CardJSONCONTEXT SCREEN ONLYBoundary: Dataset registration does not convert context evidence into DMD perturbation-response outcome. |
| GSE272233DMD-locus CRISPR-correction transcript reference | Duchenne muscular dystrophyDMD-locus correction reference | bulk RNA expression21 samples; 3 per reported group | Open GSE272233Source repository and publication terms apply; verify at accessionSource verification: required | Dataset CardJSONORTHOGONAL REFERENCE ONLYBoundary: Dataset registration does not convert context evidence into DMD perturbation-response outcome. |
| GSE52529Human myogenic differentiation time course | Non-disease trajectory referenceprimary skeletal myoblast differentiation | single-cell expression271 cells | Open GSE52529Source repository and package terms apply; verify at accessionSource verification: required | Dataset CardJSONTRAJECTORY REFERENCE ONLYBoundary: Dataset registration does not convert context evidence into DMD perturbation-response outcome. |
| GSE133344CRISPRa single and combinatorial calibration reference | Non-muscle method calibrationK562 method-calibration reference | single-cell perturbation expression287 perturbations; 112 singles; 132 pairs | Open GSE133344Source repository and publication terms apply; verify at accessionSource verification: required | Dataset CardJSONMETHOD CALIBRATION ONLYBoundary: Dataset registration does not convert context evidence into DMD perturbation-response outcome. |
The GSE293514 article DOI identifies the source publication; it is not the project archive DOI, which remains pending.
Machine access
Typed interfaces, explicit runtime health, and an edge-access caveat.
The application exposes versioned JSON, CORS metadata, GET/HEAD/OPTIONS semantics, manifests, and checksums. The latest source-bundled anonymous machine-route QA is BLOCKED_HTTP_403 (checked 2026-08-18, historical receipt sites-version-167-evidence-landscape). Behavior may vary by network and client; browser-visible availability and provider deploy success do not establish anonymous API availability. Application headers cannot override edge policy.
Presentation candidate sites-scoped-batch-compare-20260904, prepared 2026-09-04 (presentation candidate prepared). Current candidate deployment: EXTERNAL VERIFICATION REQUIRED. A provider receipt can be added only after rollout.
Scientific boundary
Public does not mean validated.
L1 resource records and L2 same-HepG2 observed perturbation evidence, selected L3a external-context screens, measured DMD-locus induction and correction, and sample-level external disease pathway analyses. No candidate-level DMD perturbation truth, calibrated candidate pathway prediction, L5 therapeutic evidence or clinical evidence is present. v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.