v1 release gate | NMD-VCell

V1ReleaseGate · v1 final-release freeze candidate

Integrity, legal identity, reconstruction and scientific validity are reported separately.

v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.

Open JSON gate Database-paper readiness NAR-style checklist

v1 final release freeze candidateOnly after all four external gates are structurally complete and author/institution authorization is recorded may the site label be changed to formal v1.0. That change still does not unlock P1 or P2 prediction claims.

Six non-interchangeable gate categories

A passing file check is not a passing biological prediction.

File and checksum integrityPASS

Public release bytes and archive identities only

Inspect evidence

API and schema integrityPASS

Typed static objects and schema contracts only

Inspect evidence

Cross-page project-state consistencyPASS

Stage A assignment, freeze, registration and outcome state

Inspect evidence

Legal and release identityPENDING

DOI, licences, maintainer and institutional authorization

Inspect evidence

Scientific prediction validityLOCKED

Independent DMD perturbation truth, calibration and prospective outcomes

Inspect evidence

Independent user reconstructionPARTIAL

Local route QA passes; independent clean-room reconstruction remains incomplete

Inspect evidence

Gate summary

What is complete now?

Public-object integrity checks10/10 pass

External gates complete0/4

Formal v1.0 releaseLOCKED

Prediction claim stateP0 prediction infrastructure ready P1 unvalidated P2 locked

Automated integrity checks

Public-object checks

Rule	Status	Evidence	Meaning
`single_source_release_identity`	pass	api/v1.1/release_manifest.json	Internal release-object integrity gate
`analysis_core_archive_checksum`	pass	checksums.sha256	Internal release-object integrity gate
`sqlite_integrity_and_nonempty_tables`	pass	downloads/large_assets/nmd_vcell_sqlite_v0.9.2_schema1.1_20260725.sqlite/parts_manifest.tsv	Internal release-object integrity gate
`typed_canonical_api`	pass	api/v1.1/openapi.json	Internal release-object integrity gate
`bounded_candidate_decision_state`	pass	api/v1.1/genes/GFOD2.json	Internal release-object integrity gate
`v1_release_freeze_gate`	pass	api/v1.1/v1_release_gate.json	Internal release-object integrity gate
`prediction_registry_scaffold`	pass	api/v1.1/prediction_registry.json	Internal release-object integrity gate
`database_paper_policy_package`	pass	downloads/DATABASE_PAPER_READINESS.md	Internal release-object integrity gate
`external_authorization_dossier_package`	pass	downloads/V1_EXTERNAL_AUTHORIZATION_DOSSIER.md	Internal release-object integrity gate
`evidence_atlas_overlay_archive_checksum`	pass	api/v1.1/overlay_archive_identity.json	Internal release-object integrity gate

External gates

Pending inputs

Rule	Status	Required input	Owner
`permanent_doi_archive`	pending_external_action	DOI for the unchanged canonical archive	External author/institution action
`institution_approved_data_licence`	pending_institutional_approval	Approved data licence identifier and text	External author/institution action
`approved_code_licence`	pending_institutional_approval	Approved code licence identifier and text	External author/institution action
`final_maintainer_and_institution_metadata`	pending_author_input	Approved maintainer, affiliation and contact metadata	External author/institution action

Database-paper package

Objects that must move together

Publication package

api/v1.1/release_manifest.json
api/v1.1/openapi.json
api/v1.3/research-objects/registry.json
api/v1.4/project-state/DMD-MIN-PERTURBOME.json
api/v1.1/v1_release_gate.json
api/v1.1/v1_external_authorization_dossier.json
api/v1.1/prediction_registry.json
ro-crate-metadata.json
codemeta.json
checksums.sha256
downloads/nmd_vcell_data_dictionary_schema_1.1.tsv
downloads/DATABASE_PAPER_READINESS.md
downloads/NAR_DATABASE_CHECKLIST.md
downloads/DATA_AVAILABILITY.md
downloads/MAINTENANCE_POLICY.md
downloads/VERSIONING_POLICY.md
downloads/V1_EXTERNAL_AUTHORIZATION_DOSSIER.md
downloads/v1_deposit_manifest.json
downloads/v1_deposit_file_list.tsv
downloads/v1_authorization_checklist.tsv
downloads/v1_licence_maintainer_metadata_template.tsv
downloads/prediction_card.schema.json
downloads/outcome_board.schema.json
downloads/external_validation_import_template.json
downloads/v1_release_handoff_checklist.tsv
downloads/V1_EXTERNAL_GATE_HANDOFF.md
downloads/v1_external_gate_input_template.json
downloads/validate_v1_external_gates.py

Still not authorized

formal v1.0 wording before DOI/licence/maintainer gates pass
validated DMD disease prediction
clinical decision support
therapeutic or treatment-prioritization claims

Release discipline. The gate can authorize database-resource wording only. It cannot unlock P1/P2 prediction claims; those remain governed by PredictionReadiness and the empty prediction registry.