NMD-VCell Research Workbench Module: Validate / registry · evidence-to-experiment workflow NMD = neuromuscular disorders
v1.0 candidate Frozen 25 Jul 2026 DOI pending
v1.0.0-database-resource Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260729-15 v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.
Current evidence ceiling L2 observed HepG2 limited L3a context No independent DMD perturbation validation Open boundary

Prediction registry scaffold

The registry is intentionally empty: 0 registered predictions, 0 measured outcomes.

No prediction has been prospectively registered and no outcome has been measured in this release. The empty registry is an integrity state, not evidence of model failure or success.

P0 prediction infrastructure ready P1 unvalidated P2 lockedv1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release.

Current counts

No prediction claim has been unlocked

Registered predictions0
Measured outcomes0
Abstained predictions0
Passed predictions0
Failed predictions0

Schemas and templates

Ready to register future P1 evidence

Read registry README · Download TSV registration template

Locked

P1 unlock requirements

  • frozen DMD/dystrophin-deficient human myogenic or neuromuscular perturbation dataset
  • train/validation/external-test partition declared before model fitting
  • donor, isogenic-pair or perturbation unit of analysis declared
  • negative, positive and rescue/control definitions predeclared
  • primary functional endpoint and transcriptomic secondary endpoints frozen
  • baseline models, calibration, uncertainty intervals and abstention policy benchmarked
  • out-of-distribution detection and failure-mode taxonomy frozen
  • prospective prediction cards timestamped before outcome access
  • outcome board populated without relabelling failed or abstained predictions

Semantics

Empty is not negative

Do not infer model performance. No prospective prediction cards exist in this release, so there is no passed, failed or abstained disease-prediction result to interpret.