{
  "project_state_schema": "nmd-vcell-project-state/1.1",
  "object_id": "PROJECTSTATE:v1.2.0-measured-dmd-evidence:DMD-MIN-PERTURBOME:1.1",
  "supersedes": "PROJECTSTATE:v1.0.0-database-resource:DMD-MIN-PERTURBOME:1.0",
  "base_release_parent": {
    "resource_release": "v1.0.0-database-resource",
    "object_id": "PROJECTSTATE:v1.0.0-database-resource:DMD-MIN-PERTURBOME:1.0",
    "public_object": "api/v1.4/project-state/releases/v1.0.0-database-resource/DMD-MIN-PERTURBOME.json"
  },
  "current_release_context": {
    "resource_release": "v1.2.0-measured-dmd-evidence",
    "interface_build": "EA-20260817-57",
    "analysis_stages": [
      "Stage C1 candidate pathway cascade",
      "Stage C2 measured DMD context"
    ],
    "disease_modules": [
      "DMD",
      "FSHD",
      "DM1",
      "SMA"
    ],
    "candidate_dmd_response_outcomes": "0/21",
    "candidate_ranking_generated": false
  },
  "project_id": "PROJECT-NMD-0001",
  "program_id": "DMD-MIN-PERTURBOME",
  "title": "DMD Minimum Perturbome",
  "effective_at": "2026-08-06",
  "authority": "config/project_state.json",
  "lifecycle_state": "PANEL_DRAFT_ASSIGNED_SIGNOFF_PENDING",
  "lifecycle_track": "TRUTH_GENERATION",
  "editable": true,
  "next_legal_state": "PANEL_FROZEN_ENDPOINT_FROZEN_READY_FOR_REGISTRATION",
  "counts": {
    "candidate_pool": 21,
    "panel_capacity": 24,
    "assigned_slots": 24,
    "frozen_slots": 0,
    "assigned_candidate_genes": 14,
    "assigned_calibration_controls": 10,
    "prospective_holdout_role_sealed": 6,
    "registered_studies": 0,
    "experiments_running": 0,
    "registered_predictions": 0,
    "measured_outcomes": 0
  },
  "gates": {
    "slot_assignment_complete": true,
    "panel_frozen": false,
    "primary_endpoint_frozen": false,
    "minimally_important_effect_frozen": false,
    "negligible_effect_margin_frozen": false,
    "registered": false,
    "experiment_started": false
  },
  "definitions": {
    "assigned": "A target or control identity occupies a named draft panel slot. Assignment remains editable until panel freeze.",
    "frozen": "The full panel and replacement rules are checksum-locked and may change only through a versioned amendment.",
    "registered": "The immutable truth-generation Study has a timestamp, checksum and complete prespecified endpoint and decision rules. A Prediction is required only for a separately declared prediction-validation track.",
    "experiment_started": "Outcome-generating laboratory work has begun under the registered package."
  },
  "blocking_items": [
    "panel signoff and checksum freeze",
    "one primary functional endpoint",
    "minimally important effect",
    "negligible-effect margin",
    "biospecimen, institutional and laboratory approvals",
    "immutable truth-generation Study registration"
  ],
  "current_state_summary": "All 24 Stage A identities are provisionally assigned (14 candidate genes and 10 calibration controls); none is frozen or registered, and no experiment has started.",
  "claim_boundary": "A provisionally assigned panel is a prospective design object. It is not an executed experiment, measured outcome or validated DMD perturbation prediction.",
  "api_schema": "nmd-vcell-project-state-api/1.0",
  "resource_release": "v1.2.0-measured-dmd-evidence",
  "interface_build": "EA-20260817-57",
  "source_object": "config/project_state.json",
  "source_sha256": "441d52287efd78935e2d72f547b7ca503ad4d34c4167a052c1f6135a4f9b4d73",
  "public_object": "api/v1.4/project-state/DMD-MIN-PERTURBOME.json"
}