NMD-VCell Virtual Cell Evidence Engine See what is known, what is uncertain, and what to test next Module: Evidence Atlas · evidence-to-experiment workflow NMD = neuromuscular disorders
Search Data & downloads Release v1.0 candidate

Current limit: the site can compare existing evidence, but no candidate has yet been independently repeated in a DMD muscle model.

Research evidence only 21 observed HepG2 perturbations 0 independent DMD replications Boundary & release
Observed HepG2 perturbations with limited external myogenic context No validated DMD perturbation prediction v1.0.0-database-resource Frozen 25 Jul 2026 Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260730-29 DOI pending Open evidence boundary →

Cell Universe

Explore the DMD muscle system one cell context at a time.

This map separates contexts with qualified evidence from compartments that still need direct perturbation data.

Find a geneFollow a trajectory
DMD muscleCell context mapSelect a compartment
Myoblast → myotube

Myogenic lineage

Limited context

What the current release can show

  • Human myoblast fusion screen for 9 of 21 candidates
  • DMD-locus correction reference with 21 samples
  • Unperturbed 0/24/48/72-hour human-myogenic trajectory
Why prediction is lockedNo independent candidate perturbation has been repeated in a DMD muscle model.

What this means: selecting a cell type changes the evidence question; it does not invent a cell-specific response.

Follow the measured trajectory

Evidence availability checker

Choose a cell context and intervention

Measured · limited · not yet tested
Can this be answered?Not yet tested in DMD muscle
Direct evidenceObserved HepG2 response exists
Related contextLimited human-myoblast screen
Missing evidenceIndependent DMD muscle perturbation

What this means: NMD-VCell can assemble the evidence and define the next experiment, but it cannot yet emit a calibrated DMD response.

Open the evidence Design the missing experiment