Measured reference programMyogenic / contractile
Descriptive mean z-score across the frozen program panel; not a perturbation response.
Disease trajectory
Separate the trajectory we measured from the disease trajectory still missing.
A real human-myogenic time course is available. Longitudinal DMD aging and perturbation-conditioned fate are not.
Measured
GSE52529 · unperturbed reference
Human myogenic differentiation
Primary human skeletal myoblasts sampled across four physical times. This describes normal differentiation context, not DMD progression.
0 hStarting myoblasts69 cells
→24 hEarly transition74 cells
→48 hIntermediate differentiation79 cells
→72 hLater reference state49 cells
Measured reference programCell cycle / proliferation
Descriptive mean z-score across the frozen program panel; not a perturbation response.
Measured reference programMetabolic / secretory
Descriptive mean z-score across the frozen program panel; not a perturbation response.
Not measured
Future DMD trajectory
Age, disease stage and treatment-conditioned fate
No released dataset currently follows the same DMD cellular system longitudinally across age or intervention.
Early regenerative stateNot assessed longitudinally
Persistent inflammatory stateNot assessed longitudinally
Fibrotic progressionNot assessed longitudinally
Late tissue replacementNot assessed longitudinally
What this means: the site can display a measured differentiation reference, but it cannot yet simulate a 5-, 10- or 20-year-old DMD cellular state.
See the data needed to unlock prediction