NMD-VCellNeuromuscular Virtual Cell Research PlatformOutcome Ledger · Evidence → perturbation → experiment → outcomeNMD = neuromuscular disorders
For Reviewers Evidence Status Claims

Evidence Release 2026.08DMD context observedDMD candidate-conditioned prediction locked

View scientific status
Evidence freeze: 3 August 2026 P59 hold · scorer failure retained · no target score NAR working package · 6 main + 31 supplementary figures Resource: v1.2.0-measured-dmd-evidence Schema: 1.1 Open platform state → Open Trust Center → Open evidence dashboard → Open claim registry → Open release status →

Outcome Ledger · local V201 candidate

Zero is a registry state, not a biological result.

This append-only ledger projects the current registered-study, prospective-prediction and experimental-outcome registries. It preserves null, toxic, discordant, QC-failed and inconclusive returns when they eventually exist.

Inspect zero stateOpen ledger JSON
OPEN EMPTY LEDGER

No governed experiment has returned an outcome.

Zero measured outcomes means no prospective experiment has returned through the governed workflow. It is not evidence of efficacy, inefficacy or a null biological effect.

0measured records

Append-only return chain

Study → optional Prediction → Experiment → Outcome.

Truth-generation does not require a prediction. Prediction validation does. Both require an immutable registered Study before the experiment begins.

Open JSON Schema →
  1. 01Registered Study0 records
  2. 02Frozen Prediction0 records · optional for Track A
  3. 03Experimentrequires registration
  4. 04Measured Outcome0 records

First-class outcome states

Unfavorable and unresolved results remain visible.

An outcome state becomes a record only after return through the governed workflow. These labels are an allowed taxonomy, not observed results.

Open source registry →
robust_responder

Append only after a governed experiment returns and the state-specific acceptance checks pass.

dmd_specific_responder

Append only after a governed experiment returns and the state-specific acceptance checks pass.

donor_variable

Append only after a governed experiment returns and the state-specific acceptance checks pass.

state_specific

Append only after a governed experiment returns and the state-specific acceptance checks pass.

toxic_responder

Append only after a governed experiment returns and the state-specific acceptance checks pass.

null_with_equivalence_margin

Append only after a governed experiment returns and the state-specific acceptance checks pass.

discordant

Append only after a governed experiment returns and the state-specific acceptance checks pass.

qc_failure

Append only after a governed experiment returns and the state-specific acceptance checks pass.

inconclusive

Append only after a governed experiment returns and the state-specific acceptance checks pass.

Interpretation boundary

An empty ledger supports abstention only.

Does not imply: candidate efficacy · candidate inefficacy · a null effect · a completed experiment · a registered prediction.

Next action: close Experiment OS gates, register the Study immutably, execute under authority and append the result irrespective of direction.

Open Experiment OS →