Model Card Audit
Same-context perturbation baseline
This card states exactly what the model was allowed to learn, predict, evaluate and claim in this release. Architecture labels and external publications do not create local DMD prediction performance.
Input, output and current result
InputTraining folds of processed HepG2 perturbation-response deltas
→OutputHeld-out 2,000-feature mean response vector
- Training context
- One processed HepG2 CRISPRi assay context
- Held-out task
- Repeated target-level balanced folds · G0
- Current result
- Small average-error improvement; response direction is not reliable.
- Permitted use
- Same-assay technical baseline and benchmark control only
Audit axes
The model is reviewed across twelve required axes.
- model identitydeclared executed limited
- training data contextdeclared executed limited
- input feature spacedeclared executed limited
- output estimanddeclared executed limited
- held out task and splitdeclared executed limited
- permanent baselinesdeclared executed limited
- primary metricsdeclared executed limited
- current result or locked statedeclared executed limited
- leakage and grouping controlsdeclared executed limited
- calibration uncertainty and abstentiondeclared executed limited
- permitted and prohibited usesdeclared executed limited
- unlock conditiondeclared executed limited
Permanent baselines
- zero change
- training-response mean
- ridge residual
Primary metrics
- RMSE
- raw cosine
- residual cosine
Leakage control
same-task split documented; disease-transfer grouping not applicable
Calibration / OOD
not_calibrated_for_dmd_response · not_validated_for_dmd_muscle_or_patient_context
Claim boundary
What this model card does not authorize
- validated dmd disease response prediction
- therapeutic efficacy or safety prediction
- patient specific or clinical decision support
- performance inherited from external foundation models
Unlock rule: Beat simple baselines on harmonized external cell-level perturbation outcome before any transport claim. Automatic unlock is disabled.