NMD-VCell Neuromuscular Virtual Cell Research Platform Module: Models · Evidence → perturbation → experiment → outcome NMD = neuromuscular disorders

Release 2026.08DMD context observedDMD candidate-conditioned prediction not yet eligible

View scientific status
Evidence freeze: 3 August 2026 Resource: v1.2.0-measured-dmd-evidence Schema: 1.1 Open release status →

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ModelRun Release · immutable execution history

Same-context ridge residual baseline

This page publishes the frozen task, result, baseline decision, provenance receipt and prohibited uses for one completed run—including failed and no-go results.

01Frozen dataNMDVCELL-HEPG2-CRISPRI
02Task & splitG0 · repeated-fold-v2.2
03Baseline comparisonPERMANENT_BASELINE
04LIMITED_PASS_SAME_CONTEXT_ONLYRETAINED_LIMITED_BASELINE

Frozen task receipt

What was evaluated

Model
NMDVCELL-RIDGE-SAFE-2.3 · ridge-safe-v2.3
Biological context
Processed HepG2 CRISPRi perturbation-response substrate
Task
G0
Data release
NMDVCELL-HEPG2-CRISPRI
Split
repeated-fold-v2.2
Execution status
COMPLETED

Decision receipt

LIMITED_PASS_SAME_CONTEXT_ONLY

Useful as a same-assay control, not as a transport or DMD response model.

Decision state
RETAINED LIMITED BASELINE
Baseline result
Small mean-RMSE improvement over train mean; raw response direction remains unsupported.
Promoted
Yes, within its stated scope
Next action
Retain permanently on every compatible holdout.

Released result

Metrics retained in this ModelRun

Released benchmark summary and Evidence Atlas invariants.

MetricValue
mean model rmse0.11750674428366534
mean train mean rmse0.11797301624780862
mean zero rmse0.12379862654747228

Quickstart · reproduction receipt

MIGRATED SUMMARY RECEIPT

This is an audit-first quickstart. It exposes the exact JSON, known prerequisites and missing receipts; it does not invent a runnable command when code, container, data or seeds are absent.

Responsible use

Prohibited claims

  • No calibrated DMD prediction.
  • No DMD disease-response prediction.
  • No therapeutic or clinical use.
  • Do not inherit performance from the model family or an external publication.

Associated resources

Follow the result into the next decision.

Claim boundary

Completed does not mean clinically or biologically qualified.

Retain permanently on every compatible holdout.