The record has stable identity, released gene-context evidence and separate muscle/DMD context fields. Available measurements are shown as observed values, not a single target score.
Search result
ZNF133: evidence you can use now.
Measured values, source context and the next evidence-producing action are shown directly below.
Target 360
ZNF133 resolves to a usable research object.
Use this as an answer route: known evidence, computability, missing evidence and the next experiment stay connected before the complete record.
- Gene layer
- 1 gene recordIdentifier and symbol search
- Workbench layer
- Guided route availableDisease, data, model and study routes
- Next value
- Muscle-context assayAction, not ranking
Direct gene result
ZNF133
A measured CRISPRi response aggregate is available for ZNF133, with muscle and DMD context kept separate.
HGNC:12917ENSG00000125846
The search result now tells whether the current evidence can support a DMD virtual-cell response, an abstention, or only an evidence-to-study handoff.
Independent muscle-context perturbation is absent is the current decision-changing gap, so the absence becomes a concrete measurement target instead of a dead end.
Open the answer card, ask the same target in Virtual Cell, then use the planner to freeze a DMD/control perturbation study and endpoint.
- Measured perturbation
- 84 HepG2 cellsFrozen CRISPRi aggregate
- Skeletal-muscle expression
- 4.55781 TPMGTEx v8 tissue context
- DMD source direction
- Sources disagree3/4 source directions agree
- Human-myoblast fusion screen
- Assessed · no endpoint hitLFC -0.003533 · FDR 0.999999
Research readiness profile
- Disease relevance
- Context available
- Cell-context evidence
- Muscle expression observed
- Human perturbation
- Assessed in myoblast screen
- DMD perturbation
- Designable next assay
- Model eligibility
- Eligible after matched DMD truth
ZNF133 CRISPRi in a DMD/control myogenic system, paired with target engagement and the endpoint chosen before results are visible.
Matched donors, non-targeting control, reagent concordance and viability stay attached to the same decision object.
The model eligibility state changes only after a replicated DMD-relevant outcome; contextual evidence alone does not become a prediction.
Open the draft Study Card, freeze the question and endpoint, then attach outcomes to the registered object.
Next value-producing actionMuscle-context assay
Run an independent DMD/control myogenic perturbation with predeclared molecular, state and functional endpoints.
Data packageOpen the actual objects behind this search result.
The gene page is the narrative view; these links expose the reusable TSV and JSON records for analysis, review and offline replication.
Gene TSVZNF133 evidence TSVA flat, analysis-ready table of the released dataset-level evidence for this gene.Typed JSONZNF133 evidence JSONThe complete machine-readable evidence object used by the gene page and planner.Core recordZNF133 core JSONStable identifiers, evidence tier, readiness state and current action in a compact object.Atlas tableAll-gene candidate tableThe released all-gene candidate universe for offline filtering and audit work.DMD effectsDMD source-specific effectsSource-by-source DMD direction and effect summaries kept separate from prediction claims.ModulesDMD evidence modulesMulti-source evidence-module memberships that explain why a gene appears in the research layer.
1 released match; gene and curated-entry counts are reported separately.
Curated research entry points
Related workbench entry points
No curated entry-point match
Try a broader term or enter the Data Universe to browse the complete source-linked inventory.
Open Data UniverseSearch contract
Use discovery to choose the next scientific action.
Search keeps the evidence type, context and decision boundary attached to each result. It helps you choose the next record, model check or experiment; it is not a therapeutic rank.