Historical detailed audit

CALR

Current authority: Computational replication

Object IDGENE-AUDIT:v1.2.0-measured-dmd-evidence:CALR

Current gene objectGENE:v1.2.0-measured-dmd-evidence:CALR

Legacy integrated DMD priorup

Source conflict stateconflicted

DMD source audit

Observed expression and regulatory inference remain separate

Source	Evidence channel	Median effect	Contexts	Direction
dmd_single_cell_baseline_pseudobulk	observed expression	0.5926	20	Positive
dmd_single_cell_delta_did_final_labels	observed expression	-0.0377	20	Negative
sema3c_deseq2_source_state	observed expression	0.5096	9	Positive
sema3c_formal_nichenet_target_state	regulatory inference	0.6376	2	Positive

Dataset/cohort identifiers and sample-overlap flags are not yet encoded in this source object; no independence claim is made from these rows. Full numeric precision remains available in the JSON record.

Current boundary

What remains unresolved

GAP-07 · Independent computational replication is absent

The registered source-balanced successor will not treat regulatory inference as observed expression. It remains preregistered and uncomputed in this release.

Resource v1.2.0-measured-dmd-evidence · schema 1.1 · build EA-20260817-57