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NMD-VCell Research OSEvidence-to-experiment operating layer
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View: Audit
Evidence Release 2026.08DMD context observedDMD candidate-conditioned prediction locked
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Evidence freeze: 3 August 2026P59 hold · scorer failure retained · no target scoreNAR working package · 6 main + 31 supplementary figuresResource: v1.2.0-measured-dmd-evidenceSchema: 1.1Open platform stateOpen Trust CenterOpen evidence dashboardOpen claim registryOpen release status
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Historical detailed audit

CALR

Current authority: Computational replication

Object IDGENE-AUDIT:v1.2.0-measured-dmd-evidence:CALR
Current gene objectGENE:v1.2.0-measured-dmd-evidence:CALR
Legacy integrated DMD priorup
Source conflict stateconflicted

DMD source audit

Observed expression and regulatory inference remain separate

SourceEvidence channelMedian effectContextsDirection
dmd_single_cell_baseline_pseudobulkobserved expression0.592620Positive
dmd_single_cell_delta_did_final_labelsobserved expression-0.037720Negative
sema3c_deseq2_source_stateobserved expression0.50969Positive
sema3c_formal_nichenet_target_stateregulatory inference0.63762Positive

Dataset/cohort identifiers and sample-overlap flags are not yet encoded in this source object; no independence claim is made from these rows. Full numeric precision remains available in the JSON record.

Current boundary

What remains unresolved

GAP-07 · Independent computational replication is absent

The registered source-balanced successor will not treat regulatory inference as observed expression. It remains preregistered and uncomputed in this release.

Resource v1.2.0-measured-dmd-evidence · schema 1.1 · build EA-20260817-57