NMD-VCell Disease Virtual Cell Platform Specify a cell-state question, inspect computability, and design the missing test Module: Compare · evidence-to-experiment workflow NMD = neuromuscular disorders

Current limit: the site can compare existing evidence, but no candidate has yet been independently repeated in a DMD muscle model.

Research evidence only 21 prioritized candidate perturbation records 2,160 benchmark perturbation targets 0 independent DMD replications Boundary & release
21 Workbench candidates are surfaced for consideration, not ranked as validated targets 2,160 target-level perturbation responses form the frozen HepG2 benchmark substrate No validated DMD perturbation prediction v1.0.0-database-resource Frozen 25 Jul 2026 Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260730-42 DOI pending Open evidence boundary →

Three-gene evidence-gap comparison

Released comparison object · v1.0.0-database-resource

Three-gene evidence-gap comparison

3 mapped genes · immutable · no ranking generated

Object IDCMP-20260726-6ED353C09779
LifecycleRELEASED
Gene schema1.1
Object creation buildEA-20260730-42
Current interface buildEA-20260730-42

Preserved evidence dimensions

Input order preserved; actions and gaps are not collapsed into a composite score
GeneCurrent actionHighest supportedLegacy integrated DMD priorSource agreementDecision-blocking gap
ZNF133 Muscle-context assay L2 observed same context perturbation up 3/4 GAP-02 Independent muscle-context perturbation is absent
MON1A Muscle-context assay L2 observed same context perturbation up 2/4 GAP-02 Independent muscle-context perturbation is absent
GFOD2 Provisional hold · external report not yet audited L2 observed same context perturbation up 2/4 GAP-09 External quantitative evidence has not been imported and audited
Build identity. The object creation build records when the checksum-addressed payload was frozen. The current interface build only renders it and does not rewrite the payload, values or SHA-256.
Claim boundary. This comparison preserves evidence dimensions and missingness. It does not create a composite score, ranking, causal claim or therapeutic recommendation.
Cite this comparison

Object ID: CMP-20260726-6ED353C09779

Payload SHA-256: 6ed353c09779f92a51bceadd7fe0522b23a2e64d1adf81ba6f13d03b1c563abe. Stable URL: https://nmdvcell.com/resource/comparison/CMP-20260726-6ED353C09779/.