NMD-VCell Evidence & Experiment Workbench Audit DMD evidence, compare gaps, and freeze the missing test Module: Compare · evidence-to-experiment workflow NMD = neuromuscular disorders

Current limit: the site can compare existing evidence, but no candidate has yet been independently repeated in a DMD muscle model.

Research evidence only 21 prioritized candidate perturbation records 2,160 benchmark perturbation targets 250 observed human-myoblast fusion hits Prospective DMD candidate validation pending Boundary & release
21 Workbench candidates are surfaced for consideration, not ranked as validated targets 2,160 target-level perturbation responses form the frozen HepG2 benchmark substrate GSE293514 Stage B0 contributes 250 healthy-human-myoblast fusion hits and 125 individually validated genes No validated DMD perturbation prediction v1.2.0-measured-dmd-evidence Frozen 3 August 2026 Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260804-49 DOI pending Open evidence boundary →

External-context contrast · CMP-20260726-3CED4054018C

Released comparison object · v1.1.0-cascade-resource

External-context contrast

3 mapped genes · immutable · no ranking generated

Object IDCMP-20260726-3CED4054018C
LifecycleRELEASED
Gene schema1.1
Object creation buildEA-20260730-42
Current interface buildEA-20260804-49

Preserved evidence dimensions

Input order preserved; actions and gaps are not collapsed into a composite score
GeneCurrent actionHighest supportedLegacy integrated DMD priorSource agreementDecision-blocking gap
GFOD2 Provisional hold · external report not yet audited L2 observed same context perturbation up 2/4 GAP-09 External quantitative evidence has not been imported and audited
ZFP69B Verify expression L2 observed same context perturbation up 2/3 GAP-06 Expression feasibility is not verified in the intended model
CPEB1 Verify expression L2 observed same context perturbation up 2/3 GAP-06 Expression feasibility is not verified in the intended model
Build identity. The object creation build records when the checksum-addressed payload was frozen. The current interface build only renders it and does not rewrite the payload, values or SHA-256.
Claim boundary. This comparison preserves evidence dimensions and missingness. It does not create a composite score, ranking, causal claim or therapeutic recommendation.
Cite this comparison

Object ID: CMP-20260726-3CED4054018C

Payload SHA-256: 3ced4054018c3cd6e0010733f12fb2fa0b9000c05c1d51f86aa321e6f5498bd9. Stable URL: https://nmdvcell.com/resource/comparison/CMP-20260726-3CED4054018C/.