{
  "disease": "SMA",
  "supports": [
    "human neural disease/intervention response",
    "source-reported SMN2 splicing and functional rescue",
    "KIF5A downstream mechanism",
    "residual-muscle hypotheses"
  ],
  "does_not_support": [
    "global gene-expression reversal",
    "significant OXPHOS/denervation/fibrosis module claim in this reanalysis",
    "patient motor-outcome prediction",
    "combination-therapy ranking"
  ]
}