{
  "schema": "nmd-vcell-discovery-catalog/1.0",
  "updated": "2026-09-15",
  "authority_rule": "This catalog selects public entry objects. Publication status and claim ceilings are resolved from platform_state_source.json; catalog membership never changes scientific evidence.",
  "channels": [
    {
      "id": "current",
      "label": "Current platform",
      "description": "Objects that define or directly support the current public research surface."
    },
    {
      "id": "publications",
      "label": "Publication packages",
      "description": "Current manuscripts and bounded working review objects, each with its own package identity."
    },
    {
      "id": "archive",
      "label": "Historical archive",
      "description": "Frozen or superseded objects retained for citation and provenance, never presented as current."
    }
  ],
  "object_count": 19,
  "records": [
    {
      "object_id": "STATE:PLATFORM:CURRENT",
      "title": "Platform evidence status",
      "summary": "One public answer for production identity, evidence freeze, P59, publication packages and the 0/21 DMD outcome boundary.",
      "channel": "current",
      "identity_state": "CURRENT",
      "evidence_type": "status",
      "public_path": "/resource/evidence-status/",
      "machine_path": "/resource/api/v2/platform_state.json",
      "claim_ceiling": "Status and governance only; this object does not create a biological result."
    },
    {
      "object_id": "REGISTRY:CLAIMS:CURRENT",
      "title": "Claim registry and evidence graph",
      "summary": "Six versioned statements, boundaries and status records linked to their supporting evidence, limiting evidence and downstream consumers.",
      "channel": "current",
      "identity_state": "CURRENT",
      "evidence_type": "claim_registry",
      "public_path": "/resource/claims/",
      "machine_path": "/resource/api/v2/claim_registry.json",
      "related_paths": [
        {
          "label": "Evidence graph",
          "path": "/resource/api/v2/claim_graph.json"
        },
        {
          "label": "Claim diff",
          "path": "/resource/api/v2/claim_diff.json"
        }
      ],
      "claim_ceiling": "Registering six existing statements does not create a new scientific claim; new scientific claim count remains zero."
    },
    {
      "object_id": "REGISTRY:RESEARCH_ANSWERS:CURRENT",
      "title": "Virtual Cell Query Composer 2.0",
      "summary": "A source-constrained Research Answer Object that binds one structured DMD/ZNF133 question to eligibility, evidence, domain and OOD state, uncertainty, missing truth, next experiment and claim ceiling.",
      "channel": "current",
      "identity_state": "CURRENT_LOCAL_CANDIDATE",
      "evidence_type": "research_answer",
      "public_path": "/resource/question/",
      "machine_path": "/resource/api/v2/research_answer_registry.json",
      "related_paths": [
        {
          "label": "Answer schema",
          "path": "/resource/api/v2/research_answer.schema.json"
        },
        {
          "label": "Governing claims",
          "path": "/resource/claims/"
        }
      ],
      "claim_ceiling": "One registered bounded answer and zero new scientific claims; unregistered query combinations abstain without inheriting nearby evidence."
    },
    {
      "object_id": "REGISTRY:EXPERIMENT_PLANS:CURRENT",
      "title": "Experiment OS readiness plan",
      "summary": "A machine-checkable projection of the canonical Research Answer and ZNF133 Study Card that separates ready, partial and open execution gates without authorizing an experiment.",
      "channel": "current",
      "identity_state": "CURRENT_LOCAL_CANDIDATE",
      "evidence_type": "experiment_plan",
      "public_path": "/resource/experiment-os/",
      "machine_path": "/resource/api/v2/experiment_plan_registry.json",
      "related_paths": [
        {
          "label": "Experiment Plan schema",
          "path": "/resource/api/v2/experiment_plan.schema.json"
        },
        {
          "label": "Outcome Ledger",
          "path": "/resource/outcomes/"
        }
      ],
      "claim_ceiling": "Design-readiness projection only; execution and registration remain unauthorized while numeric and authority gates are open."
    },
    {
      "object_id": "REGISTRY:OUTCOME_LEDGER:CURRENT",
      "title": "Outcome Ledger",
      "summary": "An append-only projection of registered studies, prospective predictions and measured outcomes with explicit zero semantics and governed result states.",
      "channel": "current",
      "identity_state": "CURRENT_LOCAL_CANDIDATE",
      "evidence_type": "outcome_ledger",
      "public_path": "/resource/outcomes/",
      "machine_path": "/resource/api/v2/outcome_ledger.json",
      "related_paths": [
        {
          "label": "Outcome Ledger schema",
          "path": "/resource/api/v2/outcome_ledger.schema.json"
        },
        {
          "label": "Experiment OS",
          "path": "/resource/experiment-os/"
        }
      ],
      "claim_ceiling": "Zero measured outcomes means no governed experiment has returned; it is neither efficacy nor inefficacy evidence."
    },
    {
      "object_id": "CONTRACT:NAVIGATION:CURRENT",
      "title": "Research OS navigation and Trust contract",
      "summary": "Seven canonical product destinations plus a five-domain Trust Center and an explicit compatibility ledger for stable legacy routes.",
      "channel": "current",
      "identity_state": "CURRENT_LOCAL_CANDIDATE",
      "evidence_type": "information_architecture",
      "public_path": "/resource/trust/",
      "machine_path": "/resource/api/v2/navigation_contract.json",
      "related_paths": [
        {
          "label": "Evidence status",
          "path": "/resource/evidence-status/"
        },
        {
          "label": "Claim registry",
          "path": "/resource/claims/"
        }
      ],
      "claim_ceiling": "Navigation and governance discovery only; this contract creates no scientific claim, model result, experiment authorization or measured outcome."
    },
    {
      "object_id": "CONTRACT:MODEL_EVALUATION:CURRENT",
      "title": "Model Evaluation Gateway",
      "summary": "One rejection-first contract joining five model adapters, model-run admission, seven metric families and the G0–G7 sparse generalization cube.",
      "channel": "current",
      "identity_state": "CURRENT_LOCAL_CANDIDATE",
      "evidence_type": "model_evaluation_contract",
      "public_path": "/resource/model-evaluation/",
      "machine_path": "/resource/api/v2/model_evaluation_contract.json",
      "related_paths": [
        {
          "label": "Model Center",
          "path": "/resource/models/"
        },
        {
          "label": "Benchmark Suite",
          "path": "/resource/benchmarks.html"
        }
      ],
      "claim_ceiling": "Admission and evaluation governance only; zero new runs, zero DMD-calibrated models and zero new scientific claims."
    },
    {
      "object_id": "CONTRACT:DIGITAL_TISSUE:CURRENT",
      "title": "Digital Tissue hypothesis workspace",
      "summary": "A multiscale evidence map that joins released cell context, physical-time and spatial references to explicit perturbation, cross-cell and patient-calibration gaps.",
      "channel": "current",
      "identity_state": "CURRENT_LOCAL_CANDIDATE",
      "evidence_type": "digital_tissue_contract",
      "public_path": "/resource/digital-tissue/",
      "machine_path": "/resource/api/v2/digital_tissue_contract.json",
      "related_paths": [
        {
          "label": "Cell contexts",
          "path": "/resource/api/v1.1/cell_context_registry.json"
        },
        {
          "label": "Spatial tasks",
          "path": "/resource/api/v1.1/multidisease_spatial_task_registry.json"
        },
        {
          "label": "Experiment OS",
          "path": "/resource/experiment-os/"
        }
      ],
      "claim_ceiling": "Hypothesis and experiment-design layer only; no cell-cell simulation, tissue rescue, patient forecast or new scientific claim."
    },
    {
      "object_id": "RELEASE:PLATFORM:CURRENT",
      "title": "Current platform release manifest",
      "summary": "The authoritative resource, schema, evidence-freeze and hosted-object boundary for the live workbench release.",
      "channel": "current",
      "identity_state": "CURRENT",
      "evidence_type": "release",
      "public_path": "/resource/api/current/release_manifest.json",
      "claim_ceiling": "Release identity does not expand scientific claims."
    },
    {
      "object_id": "EVIDENCE:DMD:MEASURED_CONTEXT",
      "title": "Measured DMD context",
      "summary": "Correction and external pathway evidence with biological-repeat-aware analyses and an explicit candidate-validation limitation.",
      "channel": "current",
      "identity_state": "CURRENT",
      "evidence_type": "direct_measurement",
      "public_path": "/resource/measured-dmd-evidence/",
      "machine_path": "/resource/api/v1.6/measured-dmd-evidence/release-manifest.json",
      "claim_ceiling": "Measured disease context; not a measured perturbation outcome for the governed 21 candidates."
    },
    {
      "object_id": "EVIDENCE:CANDIDATE_STATE:CURRENT",
      "title": "Candidate decision state",
      "summary": "Current action states, blocking gaps and minimum next experiments for the 21 governed hypotheses; no therapeutic rank is generated.",
      "channel": "current",
      "identity_state": "CURRENT",
      "evidence_type": "computational_bridge",
      "public_path": "/resource/api/v1.1/candidate_decision_registry.json",
      "machine_path": "/resource/downloads/candidate_decision_registry.tsv",
      "claim_ceiling": "Hypothesis and next-action support only; directly measured DMD candidate outcomes remain 0/21."
    },
    {
      "object_id": "CONTRACT:PROSPECTIVE_STUDY:CURRENT",
      "title": "Study and outcome contracts",
      "summary": "Draft Study Cards plus prediction and outcome schemas for prospective registration without fabricating a registered study.",
      "channel": "current",
      "identity_state": "CURRENT",
      "evidence_type": "prospective_contract",
      "public_path": "/resource/registry",
      "machine_path": "/resource/downloads/outcome_board.schema.json",
      "claim_ceiling": "Design scaffold only; registered studies, predictions and outcomes remain zero until external events occur."
    },
    {
      "object_id": "REPRO:PORTABLE_RO_CRATE:CURRENT",
      "title": "Portable research snapshot",
      "summary": "Checksummed current APIs, tables, code and provenance assembled as a portable RO-Crate source artifact.",
      "channel": "current",
      "identity_state": "CURRENT",
      "evidence_type": "reproducibility",
      "public_path": "/resource/api/v1.1/portable_release_bundle.json",
      "claim_ceiling": "Reproducibility package; not a DOI deposit or independent scientific validation."
    },
    {
      "object_id": "PACKAGE:SCIENCE_ADVANCES:P59",
      "summary": "Current Science Advances manuscript identity. Public scope is status only because the chemical replay produced no target score.",
      "channel": "publications",
      "identity_state": "CURRENT_HOLD",
      "evidence_type": "publication",
      "public_path": "/resource/support-aware",
      "machine_path": "/resource/api/v2/publication_packages.json",
      "title": "Falsification-first evaluation separates failure ranking from utility in perturbation transfer",
      "publication_package_id": "PUB:SCIENCE_ADVANCES:P59:20260911",
      "package_status": "HOLD_PRIMARY_SCORER_FAILURE",
      "formal_submission_ready": false,
      "claim_ceiling": "The chemical replay produced no target score. The retained scorer failure is an engineering outcome, not evidence for or against perturbation-transfer performance or DMD efficacy."
    },
    {
      "object_id": "PACKAGE:NAR:CURATED_V08_STORY",
      "summary": "Current public NAR working package with six main figures, 31 supplementary figures and 47 governed members.",
      "channel": "publications",
      "identity_state": "CURRENT_WORKING",
      "evidence_type": "publication",
      "public_path": "/resource/publications/",
      "machine_path": "/resource/api/v1.1/publication_package_registry.json",
      "title": "NMD-VCell NAR curated v08 story-optimized working package",
      "publication_package_id": "PUB:NAR:CURATED_V08_STORY:20260818",
      "package_status": "WORKING_AUTHOR_REVIEW_REQUIRED_NOT_SUBMISSION_READY",
      "formal_submission_ready": false,
      "claim_ceiling": "Working author-review package; technical completeness does not confer formal submission readiness."
    },
    {
      "object_id": "PACKAGE:ADAM10:V08.7",
      "summary": "Curated v08.7 design-sensitivity package with outcomes blinded; this bounded review object is not a Disease Atlas result.",
      "channel": "publications",
      "identity_state": "WORKING_REVIEW",
      "evidence_type": "review_object",
      "public_path": "/resource/adam10-design-sensitivity/",
      "machine_path": "/resource/api/v1.1/adam10_operating_characteristics_v087.json",
      "related_paths": [
        {
          "label": "Download packet",
          "path": "/resource/downloads/nmd_vcell_adam10_design_sensitivity_v087_20260906.zip"
        },
        {
          "label": "Consistency contract",
          "path": "/resource/api/v1.1/research_consistency_contract.json"
        },
        {
          "label": "Web-PDF derivation audit",
          "path": "/resource/downloads/multidisease-v02/WEB_PUBLICATION_PDF_AUDIT.json"
        }
      ],
      "title": "ADAM10 design-sensitivity review object",
      "publication_package_id": "PUB:ADAM10:V08.7:DESIGN_SENSITIVITY",
      "package_status": "WORKING_REVIEW_OBJECT_OUTCOMES_BLINDED",
      "formal_submission_ready": false,
      "claim_ceiling": "This historical package does not define current scientific state."
    },
    {
      "object_id": "PACKAGE:DATABASE:V1.0.0",
      "summary": "Immutable database-paper publication base retained for citation and byte-level provenance.",
      "channel": "archive",
      "identity_state": "FROZEN",
      "evidence_type": "publication",
      "public_path": "/resource/releases/v1.0.0-database-resource/",
      "machine_path": "/resource/api/releases/v1.0.0-database-resource/release_manifest.json",
      "title": "Immutable v1.0.0 database-paper snapshot",
      "publication_package_id": "PUB:DATABASE:V1.0.0:FROZEN",
      "package_status": "FROZEN_HISTORICAL_PUBLICATION_BASE",
      "formal_submission_ready": false,
      "claim_ceiling": "This historical package does not define current scientific state."
    },
    {
      "object_id": "PACKAGE:SCIENCE_ADVANCES:V09.80",
      "summary": "Earlier Science Advances review packet retained as history and explicitly superseded by P59.",
      "channel": "archive",
      "identity_state": "SUPERSEDED",
      "evidence_type": "publication",
      "public_path": "/resource/api/v1.1/science_advances_manuscript_packet_v09_80.json",
      "title": "Science Advances v09.80 review packet",
      "publication_package_id": "PUB:SCIENCE_ADVANCES:V09_80:HISTORICAL",
      "package_status": "HISTORICAL_SUPERSEDED_BY_P59",
      "formal_submission_ready": false,
      "claim_ceiling": "This historical package does not define current scientific state."
    },
    {
      "object_id": "ARCHIVE:DOWNLOAD_AUDIT",
      "title": "Historical download ledger",
      "summary": "The complete versioned-file and checksum ledger for auditors who need older or internal release identities.",
      "channel": "archive",
      "identity_state": "HISTORICAL",
      "evidence_type": "audit",
      "public_path": "/resource/downloads/audit/",
      "claim_ceiling": "Provenance and recovery only; directory presence is not current-package membership."
    }
  ],
  "catalog_sha256": "558d2f7efd0cf943a81ad1e19002a4c6e04b5b3f018e8df344614704e8604d9b"
}