{
  "manifest_schema": "nmd-vcell-dmd-prior-api/1.2",
  "api_schema": "1.2",
  "resource_release": "v1.0.0-database-resource",
  "input_freeze": "2026-07-25",
  "result_freeze": "2026-07-25",
  "interface_build": "EA-20260729-15",
  "gene_count": 17921,
  "source_audit_gene_count": 17920,
  "legacy_integrated_prior_count": 17919,
  "algorithm": {
    "algorithm_schema": "nmd-vcell-dmd-prior-algorithm/1.2",
    "current_published_algorithm": {
      "algorithm_id": "dmd-prior-qweighted-context-v0.9",
      "role": "legacy_integrated_prior_and_audit_baseline",
      "status": "computed_and_frozen",
      "input_freeze": "2026-07-25",
      "result_freeze": "2026-07-25",
      "aggregation": "sign(effect) multiplied by absolute effect and clipped -log10(q); median across eligible context rows"
    },
    "registered_successor_algorithm": {
      "algorithm_id": "dmd-prior-source-balanced-v1.0",
      "role": "planned_primary_source_balanced_prior",
      "status": "preregistered_not_computed",
      "required_before_result_release": [
        "within-source aggregation frozen",
        "source-balanced aggregation frozen",
        "practical-effect threshold calibrated",
        "source dependence groups resolved",
        "five-rule multiverse computed",
        "gene-level leave-one-source-out computed"
      ]
    }
  },
  "endpoints": {
    "gene": "genes/{gene}.json",
    "sources": "sources.json",
    "concordance": "concordance.json",
    "robustness": "robustness.json",
    "practical_effect_registry": "practical_effect_registry.json",
    "conflict_taxonomy": "conflict_taxonomy.json",
    "openapi": "openapi.json"
  },
  "claim_boundary": "The frozen integrated direction is an observational prior, not causal perturbation ground truth or therapeutic guidance."
}