{
  "run_schema": "nmd-vcell-model-run/1.0",
  "interface_build": "EA-20260817-57",
  "resource_release": "v1.2.0-measured-dmd-evidence",
  "evidence_freeze": "2026-08-03",
  "run_id": "MRUN-TXPERT-CONFIG-GAT-SEED-20260712",
  "model_id": "EXTERNAL-TXPERT-CONFIG-GAT-PUBLIC-STRING",
  "model_name": "TxPert public-STRING config-gat",
  "model_version": "source-08d82ee",
  "run_role": "PREREGISTERED_ADVANCED_COMPARATOR",
  "execution_status": "COMPLETED",
  "decision_state": "ADVANCEMENT_GATE_FAILED",
  "completed_at": "2026-07-21",
  "completion_date_status": "FROZEN_EXECUTION_REPORT",
  "biological_context": "Processed HepG2 CRISPRi perturbation-response substrate",
  "task_id": "G0",
  "data_release": "NMDVCELL-HEPG2-CRISPRI-TXPERT-ADAPTER-V26",
  "split_id": "txpert-v26-frozen-seed-20260712",
  "seeds": [
    "20260712"
  ],
  "seed_status": "FIRST_SEED_COMPLETE_REMAINING_CONFIRMATORY_SEEDS_LOCKED",
  "provenance": {
    "code_revision": "08d82eea86746b044cf7531f4ec8c5f60e1cb73f",
    "code_revision_status": "PINNED_CLEAN_OFFICIAL_SOURCE",
    "container_digest": null,
    "container_digest_status": "RUNTIME_RECORDED_CONTAINER_DIGEST_NOT_FROZEN",
    "data_digests": [],
    "runtime": "Official-width config-gat with public STRING; 20 epochs; V100 recovery evaluation made zero parameter updates",
    "source_report_path": "reports/V26_MULTIMODEL_VIRTUAL_CELL_EXECUTION_REPORT_20260721.md",
    "source_report_sha256": "3b09c036563b4039c5d3061212522c6cbad41990d320a5bc32ebb89838edb8fc"
  },
  "metrics": {
    "held_out_conditions": 534,
    "global_delta_rmse": 0.115092,
    "median_delta_rmse": 0.097833,
    "median_delta_cosine": 0.346196,
    "top1_retrieval_fraction": 0.02809,
    "top5_retrieval_fraction": 0.09176,
    "train_mean_median_delta_cosine": 0.373307
  },
  "baseline_comparison": "Improved RMSE and retrieval over simple controls but missed the preregistered median-delta-cosine gate against train mean.",
  "gate": {
    "decision": "FAIL",
    "reason": "Median delta cosine 0.346196 was below the train-mean control at 0.373307.",
    "next_action": "Do not run the remaining confirmatory seeds without a new preregistration and untouched evaluation set."
  },
  "verification": "Independent recomputation passed 130/130 checks; the advancement gate remained failed.",
  "source_artifacts": [],
  "promoted_to_current_model": false,
  "claim_boundary": {
    "calibrated_dmd_prediction": false,
    "dmd_disease_response_prediction": false,
    "therapeutic_or_clinical_use": false
  },
  "stable_url": "/resource/model-run/mrun-txpert-config-gat-seed-20260712/",
  "json_url": "/resource/api/v1.1/model-runs/mrun-txpert-config-gat-seed-20260712.json"
}