{ "index_schema": "nmd-vcell-detailed-gene-index/1.2", "interface_build": "EA-20260817-57", "resource_release": "v1.2.0-measured-dmd-evidence", "page_size": 20, "record_count": 123, "records": [ { "gene": "ACTA1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "acta1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/ACTA1" }, { "gene": "ADAM10", "action": "Computational replication", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "conflicted", "gap": "GAP-07", "gap_label": "Independent computational replication is absent", "muscle": "muscle detected", "muscle_tpm": 3.1162, "screen": "Assessed · no current hit", "search": "adam10 computational replication l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked conflicted gap-07 independent computational replication is absent muscle detected assessed · no current hit", "record_url": "/resource/gene/ADAM10" }, { "gene": "ADAMDEC1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "adamdec1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/ADAMDEC1" }, { "gene": "ADCYAP1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "adcyap1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/ADCYAP1" }, { "gene": "AIF1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "aif1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/AIF1" }, { "gene": "APOA1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "apoa1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/APOA1" }, { "gene": "APOD", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "apod inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/APOD" }, { "gene": "BANK1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "bank1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/BANK1" }, { "gene": "CACNA2D3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cacna2d3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CACNA2D3" }, { "gene": "CALR", "action": "Computational replication", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "conflicted", "gap": "GAP-07", "gap_label": "Independent computational replication is absent", "muscle": "muscle detected", "muscle_tpm": 88.6307, "screen": "Assessed · no current hit", "search": "calr computational replication l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked conflicted gap-07 independent computational replication is absent muscle detected assessed · no current hit", "record_url": "/resource/gene/CALR" }, { "gene": "CCK", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cck inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CCK" }, { "gene": "CCN3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "ccn3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CCN3" }, { "gene": "CCSER1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "ccser1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CCSER1" }, { "gene": "CD83", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cd83 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CD83" }, { "gene": "CDH20", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cdh20 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CDH20" }, { "gene": "CERS4", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cers4 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CERS4" }, { "gene": "CFD", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cfd inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CFD" }, { "gene": "CHI3L1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "chi3l1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CHI3L1" }, { "gene": "CHIT1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "chit1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CHIT1" }, { "gene": "COL10A1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "col10a1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/COL10A1" }, { "gene": "COMP", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "comp inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/COMP" }, { "gene": "CPAMD8", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cpamd8 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CPAMD8" }, { "gene": "CPEB1", "action": "Verify expression", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-06", "gap_label": "Expression feasibility is not verified in the intended model", "muscle": "confirm expression", "muscle_tpm": 0.731389, "screen": "Not assessed", "search": "cpeb1 verify expression l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-06 expression feasibility is not verified in the intended model confirm expression not assessed", "record_url": "/resource/gene/CPEB1" }, { "gene": "CPNE5", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cpne5 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CPNE5" }, { "gene": "CTHRC1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cthrc1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CTHRC1" }, { "gene": "CTNNAL1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "ctnnal1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CTNNAL1" }, { "gene": "CYSLTR2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "cysltr2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/CYSLTR2" }, { "gene": "DCN", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent down", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "dcn inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent down gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/DCN" }, { "gene": "DDX19B", "action": "Computational replication", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "conflicted", "gap": "GAP-07", "gap_label": "Independent computational replication is absent", "muscle": "muscle detected", "muscle_tpm": 7.22865, "screen": "Assessed · no current hit", "search": "ddx19b computational replication l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked conflicted gap-07 independent computational replication is absent muscle detected assessed · no current hit", "record_url": "/resource/gene/DDX19B" }, { "gene": "DKK3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "dkk3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/DKK3" }, { "gene": "DLK1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "dlk1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/DLK1" }, { "gene": "DNAAF3", "action": "Verify expression", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "consistent up", "gap": "GAP-06", "gap_label": "Expression feasibility is not verified in the intended model", "muscle": "confirm expression", "muscle_tpm": 0.0755557, "screen": "Not assessed", "search": "dnaaf3 verify expression l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready consistent up gap-06 expression feasibility is not verified in the intended model confirm expression not assessed", "record_url": "/resource/gene/DNAAF3" }, { "gene": "DNM1", "action": "Computational replication", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-07", "gap_label": "Independent computational replication is absent", "muscle": "muscle detected", "muscle_tpm": 1.39988, "screen": "Not assessed", "search": "dnm1 computational replication l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-07 independent computational replication is absent muscle detected not assessed", "record_url": "/resource/gene/DNM1" }, { "gene": "ECM1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "ecm1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/ECM1" }, { "gene": "EFNA5", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "efna5 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/EFNA5" }, { "gene": "EHMT2", "action": "Computational replication", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-07", "gap_label": "Independent computational replication is absent", "muscle": "muscle detected", "muscle_tpm": 6.40587, "screen": "Not assessed", "search": "ehmt2 computational replication l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-07 independent computational replication is absent muscle detected not assessed", "record_url": "/resource/gene/EHMT2" }, { "gene": "EMB", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "emb inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/EMB" }, { "gene": "EPB41L1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "epb41l1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/EPB41L1" }, { "gene": "EPS8L1", "action": "Verify expression", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "consistent up", "gap": "GAP-06", "gap_label": "Expression feasibility is not verified in the intended model", "muscle": "confirm expression", "muscle_tpm": 0.236384, "screen": "Not assessed", "search": "eps8l1 verify expression l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready consistent up gap-06 expression feasibility is not verified in the intended model confirm expression not assessed", "record_url": "/resource/gene/EPS8L1" }, { "gene": "ESRRG", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "esrrg inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/ESRRG" }, { "gene": "FABP3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "fabp3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/FABP3" }, { "gene": "FBN3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "fbn3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/FBN3" }, { "gene": "FCER2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "fcer2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/FCER2" }, { "gene": "FHDC1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "fhdc1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/FHDC1" }, { "gene": "FMN1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "fmn1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/FMN1" }, { "gene": "FMO1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "fmo1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/FMO1" }, { "gene": "FST", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "fst inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/FST" }, { "gene": "GABRG3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "gabrg3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/GABRG3" }, { "gene": "GAS2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "gas2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/GAS2" }, { "gene": "GFOD2", "action": "Provisional hold · external report not yet audited", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-09", "gap_label": "External quantitative evidence has not been imported and audited", "muscle": "muscle detected", "muscle_tpm": 2.94732, "screen": "Not assessed", "search": "gfod2 provisional hold · external report not yet audited l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-09 external quantitative evidence has not been imported and audited muscle detected not assessed", "record_url": "/resource/gene/GFOD2" }, { "gene": "GFPT2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "gfpt2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/GFPT2" }, { "gene": "GFRA1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "gfra1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/GFRA1" }, { "gene": "GPX3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "gpx3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/GPX3" }, { "gene": "GRID2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "grid2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/GRID2" }, { "gene": "GRM1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent down", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "grm1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent down gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/GRM1" }, { "gene": "GRP", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "grp inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/GRP" }, { "gene": "HIF3A", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "hif3a inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/HIF3A" }, { "gene": "IL33", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "il33 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/IL33" }, { "gene": "IL3RA", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "il3ra inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/IL3RA" }, { "gene": "INTS13", "action": "Risk/context review", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "consistent up", "gap": "GAP-08", "gap_label": "Safety and dependency context blocks escalation", "muscle": "muscle detected", "muscle_tpm": 10.9911, "screen": "Not assessed", "search": "ints13 risk/context review l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready consistent up gap-08 safety and dependency context blocks escalation muscle detected not assessed", "record_url": "/resource/gene/INTS13" }, { "gene": "KCNT2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "kcnt2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/KCNT2" }, { "gene": "KCTD8", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "kctd8 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/KCTD8" }, { "gene": "LMO2", "action": "Computational replication", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-07", "gap_label": "Independent computational replication is absent", "muscle": "muscle detected", "muscle_tpm": 15.237, "screen": "Not assessed", "search": "lmo2 computational replication l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-07 independent computational replication is absent muscle detected not assessed", "record_url": "/resource/gene/LMO2" }, { "gene": "LPL", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "lpl inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/LPL" }, { "gene": "LST1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "lst1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/LST1" }, { "gene": "LTBP1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "ltbp1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/LTBP1" }, { "gene": "MAL", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "mal inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MAL" }, { "gene": "MEST", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "mest inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MEST" }, { "gene": "MLXIPL", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "mlxipl inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MLXIPL" }, { "gene": "MMP27", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "mmp27 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MMP27" }, { "gene": "MON1A", "action": "Muscle-context assay", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "conflicted", "gap": "GAP-02", "gap_label": "Independent muscle-context perturbation is absent", "muscle": "muscle detected", "muscle_tpm": 8.05698, "screen": "Assessed · no current hit", "search": "mon1a muscle-context assay l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked conflicted gap-02 independent muscle-context perturbation is absent muscle detected assessed · no current hit", "record_url": "/resource/gene/MON1A" }, { "gene": "MPHOSPH6", "action": "Computational replication", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "consistent up", "gap": "GAP-07", "gap_label": "Independent computational replication is absent", "muscle": "muscle detected", "muscle_tpm": 4.94586, "screen": "Assessed · no current hit", "search": "mphosph6 computational replication l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked consistent up gap-07 independent computational replication is absent muscle detected assessed · no current hit", "record_url": "/resource/gene/MPHOSPH6" }, { "gene": "MS4A7", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "ms4a7 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MS4A7" }, { "gene": "MSR1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "msr1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MSR1" }, { "gene": "MYL1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "myl1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MYL1" }, { "gene": "MYL2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "myl2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MYL2" }, { "gene": "MYLPF", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "mylpf inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MYLPF" }, { "gene": "MYOC", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "myoc inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MYOC" }, { "gene": "MYOG", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "myog inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/MYOG" }, { "gene": "NAGLU", "action": "Risk/context review", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "conflicted", "gap": "GAP-08", "gap_label": "Safety and dependency context blocks escalation", "muscle": "muscle detected", "muscle_tpm": 8.66362, "screen": "Assessed · no current hit", "search": "naglu risk/context review l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked conflicted gap-08 safety and dependency context blocks escalation muscle detected assessed · no current hit", "record_url": "/resource/gene/NAGLU" }, { "gene": "NAV3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "nav3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/NAV3" }, { "gene": "NCAM1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "ncam1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/NCAM1" }, { "gene": "NOX5", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "nox5 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/NOX5" }, { "gene": "OPN1SW", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "opn1sw inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/OPN1SW" }, { "gene": "PADI2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "padi2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PADI2" }, { "gene": "PAK1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "pak1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PAK1" }, { "gene": "PCDH11X", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent down", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "pcdh11x inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent down gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PCDH11X" }, { "gene": "PCDH15", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "pcdh15 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PCDH15" }, { "gene": "PF4V1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "pf4v1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PF4V1" }, { "gene": "PLA2G2A", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "pla2g2a inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PLA2G2A" }, { "gene": "PLVAP", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "plvap inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PLVAP" }, { "gene": "PLXDC1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "plxdc1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PLXDC1" }, { "gene": "PRPH2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "prph2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PRPH2" }, { "gene": "PRSS23", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "prss23 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PRSS23" }, { "gene": "PTGER3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "ptger3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/PTGER3" }, { "gene": "RAC3", "action": "Risk/context review", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-08", "gap_label": "Safety and dependency context blocks escalation", "muscle": "confirm expression", "muscle_tpm": 0.339463, "screen": "Not assessed", "search": "rac3 risk/context review l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-08 safety and dependency context blocks escalation confirm expression not assessed", "record_url": "/resource/gene/RAC3" }, { "gene": "RCN1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent up", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "rcn1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent up gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/RCN1" }, { "gene": "RGCC", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "rgcc inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/RGCC" }, { "gene": "RGS17", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "rgs17 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/RGS17" }, { "gene": "RGS4", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "rgs4 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/RGS4" }, { "gene": "RGS7BP", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "rgs7bp inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/RGS7BP" }, { "gene": "RNASEH2C", "action": "Risk/context review", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "consistent up", "gap": "GAP-08", "gap_label": "Safety and dependency context blocks escalation", "muscle": "muscle detected", "muscle_tpm": 9.52581, "screen": "Assessed · no current hit", "search": "rnaseh2c risk/context review l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked consistent up gap-08 safety and dependency context blocks escalation muscle detected assessed · no current hit", "record_url": "/resource/gene/RNASEH2C" }, { "gene": "RNF8", "action": "Risk/context review", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-08", "gap_label": "Safety and dependency context blocks escalation", "muscle": "muscle detected", "muscle_tpm": 4.10534, "screen": "Not assessed", "search": "rnf8 risk/context review l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-08 safety and dependency context blocks escalation muscle detected not assessed", "record_url": "/resource/gene/RNF8" }, { "gene": "RPS15A", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "rps15a inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/RPS15A" }, { "gene": "SEMA3E", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "sema3e inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/SEMA3E" }, { "gene": "SERPINA3", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "serpina3 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/SERPINA3" }, { "gene": "SLC26A7", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "slc26a7 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/SLC26A7" }, { "gene": "SLN", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "sln inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/SLN" }, { "gene": "SPON1", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "spon1 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/SPON1" }, { "gene": "STMN2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "stmn2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/STMN2" }, { "gene": "TLR4", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "tlr4 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/TLR4" }, { "gene": "TMEM178B", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "tmem178b inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/TMEM178B" }, { "gene": "TNC", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "tnc inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/TNC" }, { "gene": "TNNC2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "tnnc2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/TNNC2" }, { "gene": "TRIM67", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "consistent down", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "trim67 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready consistent down gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/TRIM67" }, { "gene": "TSPAN8", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "tspan8 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/TSPAN8" }, { "gene": "VIPR2", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "vipr2 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/VIPR2" }, { "gene": "WDR4", "action": "Risk/context review", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "consistent up", "gap": "GAP-08", "gap_label": "Safety and dependency context blocks escalation", "muscle": "muscle detected", "muscle_tpm": 4.15911, "screen": "Assessed · no current hit", "search": "wdr4 risk/context review l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked consistent up gap-08 safety and dependency context blocks escalation muscle detected assessed · no current hit", "record_url": "/resource/gene/WDR4" }, { "gene": "WDR5B", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "wdr5b inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/WDR5B" }, { "gene": "ZBTB16", "action": "Inspect bounded evidence", "evidence": "L1 resource record", "evidence_tier": "G1", "evidence_tier_label": "G1 · DMD-background evidence", "evidence_tier_plain_language": "The gene has DMD-background evidence, but no qualifying perturbation response.", "prediction_readiness": "R0", "prediction_readiness_label": "R0 · evidence annotation only", "prediction_readiness_plain_language": "The current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate.", "prediction_readiness_state": "not_prediction_ready", "dmd": "conflicted", "gap": "GAP-01", "gap_label": "Direct target-level perturbation evidence is absent", "muscle": "not available", "muscle_tpm": null, "screen": "Not assessed", "search": "zbtb16 inspect bounded evidence l1 resource record g1 g1 · dmd-background evidence the gene has dmd-background evidence, but no qualifying perturbation response. r0 r0 · evidence annotation only the current release can describe the gene and evidence gaps, but cannot use it as a prediction substrate. not_prediction_ready conflicted gap-01 direct target-level perturbation evidence is absent not available not assessed", "record_url": "/resource/gene/ZBTB16" }, { "gene": "ZFP69B", "action": "Verify expression", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-06", "gap_label": "Expression feasibility is not verified in the intended model", "muscle": "confirm expression", "muscle_tpm": 0.155208, "screen": "Not assessed", "search": "zfp69b verify expression l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-06 expression feasibility is not verified in the intended model confirm expression not assessed", "record_url": "/resource/gene/ZFP69B" }, { "gene": "ZNF133", "action": "Muscle-context assay", "evidence": "L2 observed same context perturbation", "evidence_tier": "G4", "evidence_tier_label": "G4 · muscle-context screen, not DMD replication", "evidence_tier_plain_language": "The gene has a muscle-context screen in addition to non-DMD perturbation evidence, but still lacks independent DMD muscle replication.", "prediction_readiness": "R2", "prediction_readiness_label": "R2 · muscle-context bridge evidence", "prediction_readiness_plain_language": "The gene has non-DMD perturbation evidence plus muscle-context screening evidence, but still lacks DMD-context perturbation outcome.", "prediction_readiness_state": "context_bridge_ready_dmd_prediction_locked", "dmd": "conflicted", "gap": "GAP-02", "gap_label": "Independent muscle-context perturbation is absent", "muscle": "muscle detected", "muscle_tpm": 4.55781, "screen": "Assessed · no current hit", "search": "znf133 muscle-context assay l2 observed same context perturbation g4 g4 · muscle-context screen, not dmd replication the gene has a muscle-context screen in addition to non-dmd perturbation evidence, but still lacks independent dmd muscle replication. r2 r2 · muscle-context bridge evidence the gene has non-dmd perturbation evidence plus muscle-context screening evidence, but still lacks dmd-context perturbation outcome. context_bridge_ready_dmd_prediction_locked conflicted gap-02 independent muscle-context perturbation is absent muscle detected assessed · no current hit", "record_url": "/resource/gene/ZNF133" }, { "gene": "ZNF236", "action": "Risk/context review", "evidence": "L2 observed same context perturbation", "evidence_tier": "G3", "evidence_tier_label": "G3 · non-DMD perturbation evidence", "evidence_tier_plain_language": "A perturbation was observed outside a DMD muscle model, so it can guide hypothesis triage but not DMD prediction.", "prediction_readiness": "R1", "prediction_readiness_label": "R1 · non-DMD perturbation substrate", "prediction_readiness_plain_language": "The gene has an observed perturbation in a non-DMD context; it can support hypothesis triage, not DMD response prediction.", "prediction_readiness_state": "hypothesis_triage_ready_not_dmd_prediction_ready", "dmd": "conflicted", "gap": "GAP-08", "gap_label": "Safety and dependency context blocks escalation", "muscle": "muscle detected", "muscle_tpm": 2.00686, "screen": "Not assessed", "search": "znf236 risk/context review l2 observed same context perturbation g3 g3 · non-dmd perturbation evidence a perturbation was observed outside a dmd muscle model, so it can guide hypothesis triage but not dmd prediction. r1 r1 · non-dmd perturbation substrate the gene has an observed perturbation in a non-dmd context; it can support hypothesis triage, not dmd response prediction. hypothesis_triage_ready_not_dmd_prediction_ready conflicted gap-08 safety and dependency context blocks escalation muscle detected not assessed", "record_url": "/resource/gene/ZNF236" } ] }