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object", "license state", "checksum", "claim ceiling" ], "statistical_rule": "Cells are nested observations. Donor, line, biopsy, culture or independent perturbation unit must remain the inferential unit for disease-level claims.", "readiness_rule": "A dataset is model-ready only when source objects, feature identity, sample mapping, license state and checksum are complete; discovery or pilot artifacts do not qualify.", "direct_truth_rule": "Disease-state, organoid, correction and healthy-myoblast screen data remain context references and do not create direct candidate-level DMD perturbation truth." }, "current_decision": "Use GSE277637 as the line-aware organoid context object and GSE288958 as a bounded, read-only, sample-aware biopsy reference. GSE288958 independent doublet and annotation audits are complete as sensitivity/disagreement layers; ambient RNA and author-exact reprocessing remain explicitly open, and disease-effect/model-label uses remain locked. Keep GSE293514 as a bounded muscle screen until exact feature and guide identity is restored.", "claim_boundary": "This intake registry distinguishes local files, derived results, pilot artifacts and missing source objects. It does not grant a dataset model-ready status merely because its GEO accession is public." }