{
  "lineage_schema": "nmd-vcell-benchmark-lineage/1.0",
  "object_id": "LINEAGE:v1.2.0-measured-dmd-evidence:HEPG2-2160X2000",
  "interface_build": "EA-20260817-57",
  "resource_release": "v1.2.0-measured-dmd-evidence",
  "benchmark_id": "HEPG2-CRISPRI-2160-TARGET-2000-FEATURE",
  "reproducibility_class": "AUDIT_REPRODUCIBLE_NOT_SOURCE_RECONSTRUCTIBLE",
  "stages": [
    {
      "stage": "Raw source",
      "state": "SOURCE_IDENTITY_REQUIRED",
      "input_hash": null,
      "output_hash": null,
      "public_object": null
    },
    {
      "stage": "Source accession",
      "state": "PRIMARY_PUBLIC_ACCESSION_NOT_RECORDED",
      "input_hash": null,
      "output_hash": null,
      "public_object": null
    },
    {
      "stage": "Immutable source object",
      "state": "SOURCE_H5AD_NOT_IN_PUBLIC_RELEASE",
      "input_hash": null,
      "output_hash": null,
      "public_object": null
    },
    {
      "stage": "Cell QC",
      "state": "AUDITABLE_FROM_PROCESSED_OBJECTS",
      "input_hash": null,
      "output_hash": null,
      "public_object": "/resource/models_methods"
    },
    {
      "stage": "Target aggregation",
      "state": "RELEASED_DERIVED_OBJECTS",
      "input_hash": null,
      "output_hash": null,
      "public_object": "/resource/api/v1.1/model_run_registry.json"
    },
    {
      "stage": "HVG selection",
      "state": "EXACT_SELECTION_LOG_REQUIRED",
      "input_hash": null,
      "output_hash": null,
      "public_object": null,
      "response_coordinates": 2000
    },
    {
      "stage": "Frozen benchmark matrix",
      "state": "RELEASED",
      "input_hash": null,
      "output_hash": null,
      "public_object": "/resource/benchmarks",
      "perturbation_targets": 2160
    },
    {
      "stage": "Split manifest and ModelRun",
      "state": "RELEASED_AUDITABLE",
      "input_hash": null,
      "output_hash": null,
      "public_object": "/resource/api/v1.1/model_run_registry.json"
    }
  ],
  "upgrade_requirements": [
    "Record the primary public accession or an explicit non-public source authority.",
    "Deposit the immutable source H5AD or an equivalent source object with SHA-256.",
    "Release the original delta store and the exact HVG-selection log.",
    "Bind every transformation to input hash, code commit, parameters, software environment and output hash."
  ],
  "claim_boundary": "The released benchmark can be audited from frozen derived objects and ModelRun receipts, but the response panel cannot be independently rebuilt from the raw source layer."
}