{
  "schema": "nmd-vcell-adam10-registration-readiness-v08.8/1.0",
  "artifact_id": "NMDVCELL-DMD-ADAM10-REGISTRATION-BRIDGE-v08.8",
  "created_at": "2026-09-06",
  "status": "BLOCKED_39_INPUTS_ZERO_OUTCOMES",
  "resource_release": "v1.2.0-measured-dmd-evidence",
  "interface_build": "EA-20260817-57",
  "counts": {
    "formal_lock_blockers": 39,
    "generated_randomization_assignments": 0,
    "registered_v088_amendments": 0,
    "observed_adam10_outcomes": 0,
    "formal_unlocks": 0
  },
  "sample_size_verdict": {
    "stage_a": "Two named model pairs can calibrate feasibility and endpoint variance only.",
    "stage_b": "Pair count cannot be frozen until endpoint-specific variance, minimum meaningful effect, equivalence margin and target operating characteristic are approved.",
    "biological_n": "independent model pairs for generalization; cells, wells, guides and technical aliquots are not independent n"
  },
  "objects": {
    "formal_parameter_lock": "/resource/api/v1.1/adam10_formal_parameter_lock_template_v088.json",
    "study_amendment": "/resource/api/v1.1/adam10_pilot_preregistration_v088.json",
    "randomization_contract": "/resource/api/v1.1/adam10_randomization_contract_v088.json",
    "outcome_ingestion_contract": "/resource/api/v1.1/adam10_outcome_ingestion_contract_v088.json",
    "completion_workbench": "/resource/adam10-formal-lock/",
    "packet": "/resource/downloads/nmd_vcell_adam10_registration_scaffold_v088_20260906.zip",
    "prior_workbench_registry": "/resource/api/v1.1/adam10_formal_lock_workbench_v090.json",
    "workbench_registry": "/resource/api/v1.1/adam10_formal_lock_workbench_v091.json"
  },
  "next_transition": "Named authorities resolve and sign all formal-lock inputs, attach Stage A evidence, freeze a checksum and externally register the amendment before randomization generation.",
  "formal_unlocks": [],
  "claim_boundary": "No v08.8 amendment is registered; no randomization or outcome exists; wet-lab execution remains unauthorized."
}